iWorx systems, recorders and software have been used for recording ERGs in rodents and insects.
ERG in Rodents
Samuels, Ivy S., et al. “Exclusion of Aldose Reductase as a mediator of ERG deficits in a mouse model of diabetic eye disease.” Visual neuroscience 29.06 (2012): 267-274.
Wu, Jiang, et al. “Contribution of Kir4. 1 to the mouse electroretinogram.” Molecular vision 10 (2004): 650.
Wu, Jiang, et al. “Voltage-dependent calcium channel CaV1. 3 subunits regulate the light peak of the electroretinogram.” Journal of neurophysiology 97.5 (2007): 3731-3735.
Wu, Jiang, Alan D. Marmorstein, and Neal S. Peachey. “Functional abnormalities in the retinal pigment epithelium of CFTR mutant mice.” Experimental eye research 83.2 (2006): 424-428.
PEACHEY, NEAL S., J. BRETT STANTON, and ALAN D. MARMORSTEIN. “Noninvasive recording and response characteristics of the rat dc-electroretinogram.” Visual neuroscience 19.06 (2002): 693-701.
Marmorstein, Alan D., Neal S. Peachey, and Karl G. Csaky. “In vivo gene transfer as a means to study the physiology and morphogenesis of the retinal pigment epithelium in the rat.” Methods 30.3 (2003): 277-285.
Marmorstein, Alan D., et al. “A model of best vitelliform macular dystrophy in rats.” Investigative ophthalmology & visual science 45.10 (2004): 3733-3739.
Wu, Jiang, Neal S. Peachey, and Alan D. Marmorstein. “Light-evoked responses of the mouse retinal pigment epithelium.” Journal of neurophysiology 91.3 (2004): 1134-1142.
Wu, Jiang, et al. “Voltage-Dependent Calcium Channel Ca.” Hum. Mol. Genet (2010).
Yu, Minzhong, et al. “Age-related changes in visual function in cystathionine-beta-synthase mutant mice, a model of hyperhomocysteinemia.” Experimental eye research 96.1 (2012): 124-131.
Won, Jungyeon, et al. “Membrane frizzled-related protein is necessary for the normal development and maintenance of photoreceptor outer segments.” Visual neuroscience 25.04 (2008): 563-574.
Shen, Yi, Wan-Yu Zhang, and George CY Chiou. “Effect of naringenin on NaIO3-induced retinal pigment epithelium degeneration and laser-induced choroidal neovascularization in rats.” International journal of ophthalmology 3.1 (2010): 5.
Jiang, Wei, and G. C. Chiou. “Effects of hydralazine on NaIO3-induced rat retinal pigment epithelium degeneration.” Int J Ophthalmol 8 (2008): 1504-10.
Shen, Yi, Pei Zhuang, and George CY Chiou. “Effect of Guanabenz on Rat AMD Models and Rabbit Choroidal Blood Flow.” The open ophthalmology journal 5 (2011): 27.
Zhuang, Pei, Yi Shen, and George CY Chiou. “Effects of flavone on the oxidation-induced injury of retinal pigment epithelium cells.” International journal of ophthalmology 3.2 (2010): 99.
Samuels, Ivy S., et al. “Light-evoked responses of the retinal pigment epithelium: changes accompanying photoreceptor loss in the mouse.” Journal of neurophysiology 104.1 (2010): 391-402.
Shen, Yi, et al. “Effect of Tetramethylpyrazine on RPE degeneration, choroidal blood flow and oxidative stress of RPE cells.” International journal of ophthalmology 3.3 (2010): 205.
Dalziel, J. E., K. E. Dunstan, and S. C. Finch. “Combined effects of fungal alkaloids on intestinal motility in an in vitro rat model.” Journal of animal science 91.11 (2013): 5177-5182.
Rajashekhar, Gangaraju, et al. “Regenerative therapeutic potential of adipose stromal cells in early stage diabetic retinopathy.” PloS one 9.1 (2014): e84671.
Chabot, Christopher C., and Laura K. Webb. “Circadian rhythms of heart rate in freely moving and restrained American lobsters, Homarus americanus.” Marine and Freshwater Behaviour and Physiology 41.1 (2008): 29-41.
ERG in Insects
Krans, Jacob, Cole Gilbert, and Ron Hoy. “Teaching insect retinal physiology with newly designed, inexpensive micromanipulators.” Advances in physiology education 30.4 (2006): 254-261.
Recorder and Software
- IX-RA-834 data recorder
IX-RA-834 with 4 BNC single ended inputs, 4 transducer amplifier inputs, two iWire Digital Interfaces, High and Low Voltage Stimulators, Digital inputs, Digital Outputs, 2 Event marker ports, and ability to synchronize multiple ganged RA units.
It includes 4 transducer inputs, for recording 4 channels of Blood Pressure. Additional 4 channels of Blood Pressure can be recorded using the IA-400D amplifier and the 4 BNC inputs of the IX-RA-834.
- IX-400 Series data recorder
Single ended recorder with 4, 8, 16 channels.
- LabScribe Data Acquisition and Analysis Software
LabScribe Data acquisition and analysis software
- LabScribe ERG Analysis Software
An electroretinogram (ERG) is a recording of the electrical responses of the cells of the retina to a light stimulus. ERG parameters are detected, and functions derived from those parameters are computed