The RS-CMAP-SA is built specifically to study Compound Muscle Action Potential (CMAP) and Nerve Conduction Velocity. This system can also be used for 4-8 channels of EMG recordings, or a combination of EMG and ECG recordings. It is optimized for recording data from rodents and other small animals.
The Compound Muscle Action Potential (CMAP) refers to the collective electrical response of a muscle following stimulation of its motor nerve. CMAP studies in rodents are widely used in preclinical neuroscience and neuromuscular research to evaluate the function of motor nerves, neuromuscular junctions, and muscle. Rodent models of diseases like Amyotrophic Lateral Sclerosis (ALS), Spinal Muscular Atrophy (SMA), or Peripheral Neuropathy often use CMAPs to track disease onset and progression. After sciatic nerve crush or transection, CMAP recordings can assess the degree and timing of functional nerve recovery, and include measurements of the M-wave, the direct motor response typically analyzed in CMAP studies. Additional cursor measurements can be added to study the H-wave, or Hoffmann Reflex, which is commonly used to test reflex responses, assessing the excitability of the spinal cord reflex pathway.
LabScribe Data acquisition and analysis software
Analyze action potentials data with LabScribe
4 channel biopotential module for recording EMG, ECG and other biopotentials
C-ISO-PN5: set of 5 platinum needle electrodes
Stimulator Cable – BNC to Dual Platinum needle electrodes
Set of Two Platinum Subdermal Electrodes with High Voltage Safety Connectors
Use a stimulus channel to mark the onset of the stimulus, identify the start and stop of the peak, and measure the latency to the start of the peak and to the peak maximum.
Calculations include:
In a new collaborative whitepaper, iWorx Systems and Scantox showcase how electrophysiology-based metrics—like CMAP, MUNE, and repeated stimulation—can track neuromuscular dysfunction in SOD1 mouse models of ALS. Through this, researchers can gain powerful, translational insights into motor neuron health, disease progression, and therapeutic impact.
Choose the measurements to design a customized iWorx systems built for your needs.
In a new collaborative whitepaper, iWorx Systems and Scantox showcase how electrophysiology-based metrics—like CMAP, MUNE, and repeated stimulation—can track neuromuscular dysfunction in SOD1 mouse models of ALS. Through this, researchers can gain powerful, translational insights into motor neuron health, disease progression, and therapeutic impact.
The Compound Muscle Action Potential (CMAP) refers to the collective electrical response of a muscle following stimulation of its motor nerve. CMAP studies in rodents are widely used in preclinical neuroscience and neuromuscular research to evaluate the function of motor nerves, neuromuscular junctions, and muscle. Rodent models of diseases like Amyotrophic Lateral Sclerosis (ALS), Spinal Muscular Atrophy (SMA), or Peripheral Neuropathy often use CMAPs to track disease onset and progression. After sciatic nerve crush or transection, CMAP recordings can assess the degree and timing of functional nerve recovery.
Calculations include:
LabScribe Data acquisition and analysis software
EMG Analysis Module
4 channel biopotential module for recording EMG, ECG and other biopotentials
C-ISO-PN5: set of 5 platinum needle electrodes
Stimulator Cable – BNC to Dual Platinum needle electrodes
Set of Two Platinum Subdermal Electrodes with High Voltage Safety Connectors
See why 93 of the top 100 schools in the U.S. (as ranked by US News and World Report) are currently using iWorx equipment and software in their labs.
Join the rapidly growing community of professors, teaching assistants and students in colleges and universities around the world who are using iWorx solutions to advance the science of physiology.
We are pleased to note that more than 90 of the top 100 schools in the U.S. (as ranked by US News and World Report) are currently using iWorx equipment and software in their labs.
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