The Rodent Langendorff System is designed to sustain the cardiac function of isolated hearts with gravity-fed, constant perfusion pressure and are available in both recirculating and non-recirculating configurations. It includes three essential components: the perfusion system, temperature control unit, and oxygen supply system, all working together to support the physiological function of isolated hearts.
They come in various sizes to accommodate different heart sizes, including those of mice, rats, guinea pigs, rabbits, and cats.
This system is a comprehensive set of equipment designed to perform ex vivo cardiac perfusion experiments. Langendorff apparatuses are designed to sustain the cardiac function of isolated heart preparations through gravity-fed constant perfusion pressure.
Constant pressure perfusion allows for monitoring of variations in heart resistance and activity through changes in flow rate, making it particularly useful in ischemia-reperfusion (IR) studies, cardiac physiology, pathology, pharmacology, and myocardial biochemistry and metabolism. With its high repeatability and stability, this system ensures reliable research results.
Coming in both recirculating and non-recirculating models, these apparatuses are also available in various sizes to accommodate different species, including mouse, rat, guinea pig, rabbit, and cat.
The iWorx team is here to help—whether you have a quick question or need hands-on support. Our technical specialists offer one-on-one assistance with setup, troubleshooting, and optimizing your system.
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