The Langendorff apparatus is designed to sustain the cardiac function of isolated hearts with gravity-fed, constant perfusion pressure and are available in both recirculating and non-recirculating configurations.
They come in various sizes to accommodate different heart sizes, including those of mice, rats, guinea pigs, rabbits, and cats.
Langendorff apparatuses are designed to sustain the cardiac function of isolated heart preparations through gravity-fed constant perfusion pressure, and they come in both recirculating and non-recirculating models. Constant pressure perfusion allows for monitoring of variations in heart resistance and activity through changes in flow rate, making it particularly useful in ischemia-reperfusion (IR) studies, cardiac physiology, pathology, pharmacology, and myocardial biochemistry and metabolism. With its high repeatability and stability, this system ensures reliable research results.
These apparatuses are also available in various sizes to accommodate different species, including mouse, rat, guinea pig, rabbit, and cat.
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