iWorx offers turnkey Intracardiac Electrical Potential Recording and Measurement Systems which include data recorders, amplifiers, cables, catheters and software. Each system has been configured to address the subject being studied and acquisition requirements
iWorx offers minimally invasive 8-electrode catheters for studying intracardiac electrical potentials in the rodent. Intracardiac electrophysiology catheters allow for in depth analysis of biopotential propagation through the heart. Up to 4 regional intracardiac electrograms can be recorded simultaneously. The same catheter can be used to pace the heart while recording electrical activity.
The platinum needle electrodes can be used to record a surface ECG from the animal as well.
IX-RA-834 with 4 BNC single ended inputs, 4 transducer amplifier inputs, two iWire Digital Interfaces, High and Low Voltage Stimulators, Digital inputs, Digital Outputs, 2 Event marker ports, and ability to synchronize multiple ganged RA units.
Allows the recording of up to 8 channels of ECG, EMG or EEG from a single iWire input.
SA-TCS-6: Heater controller with a 6” x 8” heated bed for mice
SA-TCS-8: Heater controller with a 8"x10" heated bed for rats.
C-ISO-PN3 : 3 subdermal platinum needle electrodes
CATH-SCI-MO-120: 1.2F Cardiac Electrogram Catheters for mice
CATH-SCI-RO-190: 1.9F Cardiac Electrogram Catheters for rats
A-CEG-CIB: Catheter interface box and cables
C-BNC-2mmM : BNC to 2mm Male Pin cable
C-HVS-2mmM: 2 Safety Connector to 2mm Male Pin cable
C-ISO-2mmM: 3x, 2mm Male Pin to Female Safety Pin cable
LabScribe Data acquisition and analysis software with the advanced ECG analysis module.
LabScribe software is a user friendly but powerful data acquisition and analysis software. It has been cited in over 1000 papers.
Use the Built-in Stimulator for S1-S2-S3 as well as Burst stimulation protocols.
iWorx LabScribe ECG Software Module is a powerful and user-friendly tool intended to automate the analysis of ECG data from a variety of species.
Technote : Intracardiac measurements with the EP catheter, including surface ECG and S1-S2-S3 stimulation.
Li, Xin, et al. “High hydrostatic pressure induces atrial electrical remodeling through upregulation of inflammatory cytokines.” Life Sciences 242 (2020): 117209.
Chan, Yi-Hsin, et al. “Atrial fibrillation and its arrhythmogenesis associated with insulin resistance.” Cardiovascular diabetology 18.1 (2019): 125.
Lakin, Robert, et al. “Inhibition of soluble TNFα prevents adverse atrial remodeling and atrial arrhythmia susceptibility induced in mice by endurance exercise.” Journal of molecular and cellular cardiology 129 (2019): 165-173.
Zhang, Youhua, et al. “Thyroid hormone replacement therapy attenuates atrial remodeling and reduces atrial fibrillation inducibility in a rat myocardial infarction–heart failure model.” Journal of cardiac failure 20.12 (2014): 1012-1019.
Rajagopalan, Viswanathan, et al. “Safe oral triiodo-L-thyronine therapy protects from post-infarct cardiac dysfunction and arrhythmias without cardiovascular adverse effects.” PLoS One 11.3 (2016): e0151413.
Rajagopalan, Viswanathan, et al. “Modified low-dose triiodo-L-thyronine therapy safely improves function following myocardial ischemia-reperfusion injury.” Frontiers in physiology 8 (2017): 225.
Delfiner, Matthew S., et al. “Failing Hearts Are More Vulnerable to Sympathetic, but Not Vagal Stimulation–Induced, Atrial Fibrillation—Ameliorated with Dantrolene Treatment.” Journal of cardiac failure 24.7 (2018): 460-469.
Dedkov, Eduard I., et al. “Sex‐related differences in intrinsic myocardial properties influence cardiac function in middle‐aged rats during infarction‐induced left ventricular remodeling.” Physiological Reports 4.11 (2016): e12822.
Liao, Song-Yan, et al. “Overexpression of Kir2. 1 channel in embryonic stem cell-derived cardiomyocytes attenuates posttransplantation proarrhythmic risk in myocardial infarction.” Heart Rhythm 10.2 (2013): 273-282.
Join the rapidly growing community of professors, teaching assistants and students in colleges and universities around the world who are using iWorx solutions to advance the science of physiology.
We are pleased to note that more than 90 of the top 100 schools in the U.S. (as ranked by US News and World Report) are currently using iWorx equipment and software in their labs.
Quick online consultation with an Applications Specialist
We will contact you with your login info.