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Intracardiac ECG System

iWorx offers turnkey Intracardiac Electrical Potential Recording and Measurement Systems which include data recorders, amplifiers, cables, catheters and software. Each system has been configured to address the subject being studied and acquisition requirements

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Overview

iWorx offers minimally invasive 8-electrode catheters for studying intracardiac electrical potentials in the rodent. Intracardiac electrophysiology catheters allow for in depth analysis of biopotential propagation through the heart. Up to 4 regional intracardiac electrograms can be recorded simultaneously. The same catheter can be used to pace the heart while recording electrical activity.

The platinum needle electrodes can be used to record a surface ECG from the animal as well.

Applications

  • Bundle of His characterization
  • SA node characterization
  • General signal propagation
  • Endocardial ECG assessment
  • Regional atrial assessment
  • Conduction studies
  • Qualification of cardiac insult

System Includes

LabScribe software is a user friendly but powerful data acquisition and analysis software. It has been cited in over 1000 papers. 

Use the Built-in Stimulator for S1-S2-S3 as well as Burst stimulation protocols. 

LabScribe ECG Analysis Module

iWorx LabScribe ECG Software Module is a powerful and user-friendly tool intended to automate the analysis of ECG data from a variety of species.

Features:
  • Measure R-R, PR, QT, QR and QTc intervals, QRS, T, P and TP durations, P, Q, R, S, T amplitudes and ST elevation, etc…
  • Specific analysis templates are included to accurately delineate PQRST onset, durations and amplitudes
  • Custom templates can also be created based on unique ECG profiles and saved to a library for future use
  • Beat averaging and classification
  • Outlier removal based on abnormal R-R intervals, heart rate, noise and activity
  • Easily extract source data and average data as images or text files
  • Plug and play compatible with all iWorx data acquisition

More Information…

ECG Analysis Video
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Citations

Li, Xin, et al. “High hydrostatic pressure induces atrial electrical remodeling through upregulation of inflammatory cytokines.” Life Sciences 242 (2020): 117209.

Chan, Yi-Hsin, et al. “Atrial fibrillation and its arrhythmogenesis associated with insulin resistance.” Cardiovascular diabetology 18.1 (2019): 125.

Lakin, Robert, et al. “Inhibition of soluble TNFα prevents adverse atrial remodeling and atrial arrhythmia susceptibility induced in mice by endurance exercise.” Journal of molecular and cellular cardiology 129 (2019): 165-173.

Zhang, Youhua, et al. “Thyroid hormone replacement therapy attenuates atrial remodeling and reduces atrial fibrillation inducibility in a rat myocardial infarction–heart failure model.” Journal of cardiac failure 20.12 (2014): 1012-1019.

Rajagopalan, Viswanathan, et al. “Safe oral triiodo-L-thyronine therapy protects from post-infarct cardiac dysfunction and arrhythmias without cardiovascular adverse effects.” PLoS One 11.3 (2016): e0151413.

Rajagopalan, Viswanathan, et al. “Modified low-dose triiodo-L-thyronine therapy safely improves function following myocardial ischemia-reperfusion injury.” Frontiers in physiology 8 (2017): 225.

Delfiner, Matthew S., et al. “Failing Hearts Are More Vulnerable to Sympathetic, but Not Vagal Stimulation–Induced, Atrial Fibrillation—Ameliorated with Dantrolene Treatment.” Journal of cardiac failure 24.7 (2018): 460-469.

Dedkov, Eduard I., et al. “Sex‐related differences in intrinsic myocardial properties influence cardiac function in middle‐aged rats during infarction‐induced left ventricular remodeling.” Physiological Reports 4.11 (2016): e12822.

Liao, Song-Yan, et al. “Overexpression of Kir2. 1 channel in embryonic stem cell-derived cardiomyocytes attenuates posttransplantation proarrhythmic risk in myocardial infarction.” Heart Rhythm 10.2 (2013): 273-282.

Join Our Community

Join the rapidly growing community of professors, teaching assistants and students in colleges and universities around the world who are using iWorx solutions to advance the science of physiology.

We are pleased to note that more than 90 of the top 100 schools in the U.S. (as ranked by US News and World Report) are currently using iWorx equipment and software in their labs.

Meet With Us

Quick online consultation with an Applications Specialist

Design Your System

Choose the parameters you want to Measure

ECG/EKG
EMG : Number of Channels
Invasive BP : Number of Channels
Non-Invasive BP : Number of Channels
Flow : Number of Channels
Temperature: Number of Channels
Force: Number of Channels
Stimulation: Describe the type

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