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Labscribe Spike Sorting Module

The LS-SPIKE module for LabScribe Software is a Spike Sorting Analysis Module that allows users to automatically calculate parameters from Nerve spike data.

$500.00

SKU LS-SPIKE Category

Spike Sorting

Spike sorting is used in the analysis of electrophysiological data. Spike sorting algorithms use the shape(s) of waveforms collected with one or more electrodes to distinguish the activity of one or more neurons from background electrical noise.

Spike sorting refers to the process of assigning spikes to different neurons. The exact time course of a spike event as recorded by the electrode depends on the size and shape of the neuron, the position of the recording electrode relative to the neuron, etc. These electrodes, positioned outside of the cells in the tissue, however, often ‘see’ the spikes generated by several neurons in their vicinity. Since the spike shapes are unique and quite reproducible for each neuron it can be used to distinguish spikes produced by different neurons, i.e. to separate the activity produced by each.

 

Spike Sorting Filter

Identify Spikes

Filter the raw data to remove noise.

Use marks to mark identify the regions of interest such as baseline, stimulus etc.

Analyze a selection or the complete data file.

Sort the various spikes into types using the height and width of the spike .

spike sorting discriminator

Measurements

View the Average spike for each type and calculate various parameters for each type such as:

  • Type of the Spike
  •  Average Height of the spikes
  •  Average Width of the spikes
  •  Mean Frequency of the spikes during the Baseline period
  •  Mean Frequency of the spikes during the Stimulus period
  • Mean Frequency of the spikes during the Response period
  • Mean Period between the spikes during the Baseline period
  • Mean Period between the spikes during the Stimulus period
  • Mean Period between the spikes during the Response period
  • Mean Count of the spikes during the Baseline period
  • Mean Count of the spikes during the Stimulus period
  • Mean Count of the spikes during the Response period
spike sorting average spike

Histogram

Set the Bin Size for the histograms. The Histogram displays the number of spikes in a bin vs time.


The Data set can be marked for 3 regions, Baseline, Stimulus and Recovery. Choose the marks in the record corresponding to the 3 regions. Marking the data into these regions helps in the analysis, since typically we want to see the difference from baseline when a stimulus occurs and then we want to see how fast the recovery takes place.

spike sorting histogram

Design Your System

Choose the parameters you want to Measure

ECG/EKG
EMG : Number of Channels
Invasive BP : Number of Channels
Non-Invasive BP : Number of Channels
Flow : Number of Channels
Temperature: Number of Channels
Force: Number of Channels
Stimulation: Describe the type

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