Pressure-volume (PV) loops have become the gold standard for studying myocardial contractility, compliance, muscle energetics and other quantitative measures of cardiac function. Typical applications for PV loops include heart failure studies, gene therapy and manipulation protocols and pharmacology studies.
iWorx offers a comprehensive acquisition and analysis solution for PV loop experiments. The foundation of these systems is the LabScribe Pressure-Volume Loop Module which allows for real-time display and analysis of elastance and compliance curves providing instant feedback on the quality of occlusions being performed. Unlike other software offerings for PV analysis, all the acquisition and analysis takes place within one program providing seamless and time saving options for generating data for publication.
The LabScribe PV Loop Module can be used to analyze pressure-volume data from any source including conductance catheters, admittance catheters, echo ultrasound systems or sonomicrometry dimension crystals. Data from other recorders and compatible echo ultrasound systems can be imported into LabScribe using the import module for analysis.
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LS-PVL: iWorx Pressure Volume Loop Software Module is a plug-in software module for iWorx data acquisition systems that performs pressure volume loop analysis for hemodynamic research in animals. The software module provides a powerful and easy to use tool for investigators to measure and analyze the hemodynamic parameters of cardiac and pulmonary pressure and volume data acquired by an iWorx recorder.
Cardiac cycle parameters that can be monitored online are:
Further analysis can be performed offline, such as selecting cycles, calculating Pressure-Volume Area, Potential Energy, Cardiac Efficiency, and plotting PV Loops, PRSW, Max dp vs EDV, PVA vs EDV, PVA vs ESP, can be performed. The data and graphs can be copied or exported to the built-in Journal or any external program.
The software module is plug and play compatible with all iWorx Data Acquisition and Analysis Modules.
Detailed information about using the modules is in the LabScribe Manual
LS-TXT The iWorx Import Module enables import of data in text format that was recorded in any other data acquisition program. The module also allows the researcher to use the analysis functions in LabScribe software on data they may previously recorded with another a different program.
LS-BP The LabScribe Blood Pressure Module acquires and analyzes data from blood pressure transducers. Data can be analyzed from ventricular and arterial signals in real-time. The software automatically calculates common indices of function from the blood pressure signal where it can easily be exported to another program for further analysis.
IX-RA-834 with 4 BNC single ended inputs, 4 transducer amplifier inputs, two iWire Digital Interfaces, High and Low Voltage Stimulators, Digital inputs, Digital Outputs, 2 Event marker ports, and ability to synchronize multiple ganged RA units.
Data Aquisition Systems are economical, high performance 4, 8 and 16 channel data recorders for use with a broad range of amplifiers. The recorders offer 16-bit resolution at maximum data collection speeds up to 10 KHz, making them appropriate for most research applications.
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